| 1-1 | Lexi Aranda (SIUE) def. Regina Espindola (IOWAST) 6-4, 6-4 |
| 2-1 | Morgan Steffes (SIUE) def. Claudia Toledo (IOWAST) 6-2, 6-4 |
| 3-1 | Margarita Timakova (IOWAST) def. Tiffany Hollebeck (SIUE) 2-6, 6-4, 12-10 |
| 4-1 | Callaghan Adams (SIUE) def. Karen Alvarez (IOWAST) 6-3, 4-6, 10-6 |
| 5-1 | Ann-Christine Link (SIUE) def. Natalie Phippen (IOWAST) 2-6, 6-3, 10-5 |
| 1-2 | Eleonore Tchakarova (SLUW) def. Lexi Aranda (SIUE) 6-4, 7-6 |
| 2-2 | Morgan Steffes (SIUE) def. Cassie McKenzie (SLUW) 6-2, 6-4 |
| 3-2 | Tiffany Hollebeck (SIUE) def. Mariluz Rojo Domingo (SLUW) 4-6, 7-6, 10-6 |
| 4-2 | Callaghan Adams (SIUE) def. Liera Bender (IOWAST) 6-4, 6-3 |
| 5-2 | Karen Alvarez (IOWAST) def. Ann-Christine Link (SIUE) 3-6, 6-3, 10-3 |
| 1-3 | Samantha Budai (IOWAST) def. Lexi Aranda (SIUE) 6-1, 6-4 |
| 2-3 | Morgan Steffes (SIUE) def. Margarita Timakova (IOWAST) 6-7, 6-1, 10-8 |
| 3-3 | Tiffany Hollebeck (SIUE) def. Annabella Bonadonna (IOWAST) 6-3, 6-3 |
| 4-3 | Erin Freeman (IOWAST) def. Callaghan Adams (SIUE) 7-5, 6-3 |
| 5-3 | Ann-Christine Link (SIUE) def. Liera Bender (IOWAST) 6-3, 3-6, 10-5 |
| 1-4 | Maty Cancini (IOWAST) def. Lexi Aranda (SIUE) 6-3, 6-4 |
| 2-4 | Morgan Steffes (SIUE) def. Regina Espindola (IOWAST) 7-5, 4-6, 11-9 |
| 3-4 | Tiffany Hollebeck (SIUE) def. Erin Freeman (IOWAST) 6-1, 7-5 |
| 4-4 | Callaghan Adams (SIUE) def. Natalie Phippen (IOWAST) 6-7 (5-7), 7-6 (7-4), 10-6 |
| 5-4 | Annabella Bonadonna (IOWAST) def. Ann-Christine Link (SIUE) 6-2, 6-2 |
