| Q1 | Reinicke, Vanessa (SIUE) def. BREMEL, Madeline (STMN) 6-1, 6-1 |
| Q1 | HLACIKOVA, Daniela (SEMO) def. Thibault, Maria (SIUE) 6-7 (0-4), 7-5, 10-2 |
| Q1 | HAAGENSEN, Mille (DRAKE) def. Vizcardo, Melissa (SIUE) 7-5, 4-6, 10-7 |
| Q1 | Hochstatter, Amber (SIUE) def. SNEZHKO, Nicole (STMN) 6-2, 6-2 |
| Q1 | Lambrechts, Jill (SIUE) def. Lorena Cardoso (UNI) 7-5, 6-1 |
| Q1 | Perez, Fabiola (SIUE) def. WHITAKER, Clara (WSU) 6-1, 6-2 |
| Q1 | VASUPONGCHAI, Yada (UCA) def. Sporing, Caitlyn (SIUE) 6-0, 6-0 |
| Q2 | SAID, Dalila (UMN) def. Reinicke, Vanessa (SIUE) 6-1, 6-4 |
| Q2 | DANILCHENKO, Anfisa (UMN) def. Hochstatter, Amber (SIUE) 6-1, 6-2 |
| Q2 | PEREZ, Mariona (SLU) def. Lambrechts, Jill (SIUE) 6-4, 7-6 (7-0) |
| Q2 | GILLAS, Samantha (IOWA) def. Perez, Fabiola (SIUE) 6-4, 6-4 |
| QC | WALCZAK, Daria (DRAKE) def. Thibault, Maria (SIUE) 6-3, 6-0 |
| QC | Vizcardo, Melissa (SIUE) def. TALAVERA, Regina (STMN) 6-2, 6-0 |
| QC | Sporing, Caitlyn (SIUE) def. DI GIULIO, Alexia (OMA) 2-6, 6-3, 10-7 |
| R128 | Schifano, Jordan (SIUE) def. GILLAS, Samantha (IOWA) 6-3, 6-2 |
| R64 | NOVAK, Kristina (NEB) def. Schifano, Jordan (SIUE) 6-2, 6-1 |
| E2 | HAAGENSEN, Mille (DRAKE) def. Hochstatter, Amber (SIUE) 6-0, 6-2 |
| E3 | Reinicke, Vanessa (SIUE) def. JANSSON, Andrea (NDAK) 6-1, 6-1 |
| E3 | ZDRAVKOVIC, Nina (NDAK) def. Schifano, Jordan (SIUE) 6-3, 0-6, 10-3 |
| E3 | Hochstatter, Amber (SIUE) def. RIZZA, Lucia (NDAK) 6-7 (0-7), 6-3, 10-8 |
| E3 | Perez, Fabiola (SIUE) def. BOWLES, Charlotte (NDAK) 6-3, 6-1 |
| E4 | Lambrechts, Jill (SIUE) def. HEINITZ, Nore (NDAK) 5-7, 6-3, 10-2 |
